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SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Turmeric ExtractCurcuma longa (Rhizome)(95% [475 mg] Total Curcuminoids)
500 mg
†
Top Medical Research Studies
9
Curcumin inhibits UTI bacteria
Inhibition of biofilm development of uropathogens by curcumin - an anti-quorum sensing agent from Curcuma longa.
Highly relevant to UTI treatments
We examined the potential of curcumin, the active ingredient in turmeric, to combat urinary tract infections (UTIs), which are often caused by bacteria forming biofilms. This study specifically looked at how curcumin could interfere with the quorum sensing (QS) systems of uropathogens like Escherichia coli and Pseudomonas aeruginosa.
Our research found that curcumin effectively inhibited the formation of biofilms by these bacteria and was even able to disrupt existing mature biofilms. Using light and confocal laser scanning microscopy, we observed these effects firsthand.
Additionally, we noted that treatment with curcumin reduced important QS-dependent activities in these bacteria, such as exopolysaccharide and alginate production, as well as their swimming and swarming abilities. Remarkably, curcumin also increased the effectiveness of standard antibiotics against these uropathogens, making it a promising option for enhancing current UTI treatments.
Our research found that curcumin effectively inhibited the formation of biofilms by these bacteria and was even able to disrupt existing mature biofilms. Using light and confocal laser scanning microscopy, we observed these effects firsthand.
Additionally, we noted that treatment with curcumin reduced important QS-dependent activities in these bacteria, such as exopolysaccharide and alginate production, as well as their swimming and swarming abilities. Remarkably, curcumin also increased the effectiveness of standard antibiotics against these uropathogens, making it a promising option for enhancing current UTI treatments.
Read More
8
Curcumin complex shows antibacterial promise
Curcumin-sulfobutyl-ether beta cyclodextrin inclusion complex: preparation, spectral characterization, molecular modeling, and antimicrobial activity.
Strong relevance to UTI treatment
We explored the effectiveness of curcumin, a natural compound found in turmeric, as a potential treatment for urinary tract infections (UTIs). Given the rising concern over antibiotic resistance, it's crucial to investigate alternative therapies, and curcumin's remarkable properties have caught our attention.
In this study, we created a complex of curcumin with sulfobutyl ether-β-cyclodextrin to enhance its solubility and bioavailability. Our findings from phase solubility studies and spectral analysis showed that curcumin was successfully encapsulated within the cyclodextrin. This complex aimed to maximize curcumin's therapeutic potential and make it more effective against bacteria.
The antimicrobial effectiveness was tested through a disc diffusion method. Interestingly, we observed that the curcumin-cyclodextrin complex exhibited significant antimicrobial activity, showing a zone of inhibition against Escherichia coli and Staphylococcus aureus—two key bacteria involved in UTIs. This result was compelling since curcumin alone exhibited no antibacterial effect.
Ultimately, our study suggests that the curcumin-cyclodextrin complex holds promise as a potential alternative for treating UTIs. By offering a new strategy against bacterial infections, it could be a significant step in addressing antibiotic resistance.
In this study, we created a complex of curcumin with sulfobutyl ether-β-cyclodextrin to enhance its solubility and bioavailability. Our findings from phase solubility studies and spectral analysis showed that curcumin was successfully encapsulated within the cyclodextrin. This complex aimed to maximize curcumin's therapeutic potential and make it more effective against bacteria.
The antimicrobial effectiveness was tested through a disc diffusion method. Interestingly, we observed that the curcumin-cyclodextrin complex exhibited significant antimicrobial activity, showing a zone of inhibition against Escherichia coli and Staphylococcus aureus—two key bacteria involved in UTIs. This result was compelling since curcumin alone exhibited no antibacterial effect.
Ultimately, our study suggests that the curcumin-cyclodextrin complex holds promise as a potential alternative for treating UTIs. By offering a new strategy against bacterial infections, it could be a significant step in addressing antibiotic resistance.
Read More
8
Curcumin aids chronic UTI treatment
Intervention effect and mechanism of curcumin in chronic urinary tract infection in rats.
Direct focus on UTI treatment
In our study, we explored how curcumin, a compound found in turmeric, affects chronic urinary tract infections (UTIs) in rats. To investigate this, we set up three groups of experimental animals: a normal group, a model group that had chronic UTIs induced, and a curcumin group that received an injection of curcumin over 14 days.
We observed that curcumin treatment significantly improved the symptoms of chronic UTIs in the rats. Specifically, it helped protect renal function and reduced inflammation, as indicated by lower levels of inflammatory cytokines in the serum. Additionally, the study highlighted that curcumin influenced the expression of critical receptors related to immune response in the renal and bladder tissues.
Overall, our findings suggest that curcumin can be an effective option for managing chronic urinary tract infections by enhancing kidney health and minimizing inflammation.
We observed that curcumin treatment significantly improved the symptoms of chronic UTIs in the rats. Specifically, it helped protect renal function and reduced inflammation, as indicated by lower levels of inflammatory cytokines in the serum. Additionally, the study highlighted that curcumin influenced the expression of critical receptors related to immune response in the renal and bladder tissues.
Overall, our findings suggest that curcumin can be an effective option for managing chronic urinary tract infections by enhancing kidney health and minimizing inflammation.
Read More
Most Useful Reviews
8.3
Really good effect
I ordered it for my father, and he said it was great! It’s truly effective for treating urinary tract infection and inflammation.
Read More
8.8
Significant improvement
Great doing the job. I have suffered from chronic infections in the pelvic area, and there has been significant improvement in treating my urinary tract infection.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
9
Combination treatment prevents recurrent UTIs
Efficacy of an orally administered combination of hyaluronic acid, chondroitin sulfate, curcumin and quercetin for the prevention of recurrent urinary tract infections in postmenopausal women.
Combination treatment's impact evaluated
We investigated whether a combination of hyaluronic acid, chondroitin sulfate, curcumin, and quercetin could effectively prevent recurrent urinary tract infections (UTIs) in postmenopausal women, particularly with the added boost of local estrogen treatment. Our study involved 145 women, all with a documented history of recurrent UTIs and mild-to-moderate urogenital atrophy.
The participants were divided into three groups: one group received only vaginal estrogens, the second was treated with the natural supplement combination, and the third group received both the supplement and vaginal estrogens. We followed up with the participants over six and twelve months to assess the frequency of UTIs and overall symptom relief.
Our findings showed that the combination of hyaluronic acid, chondroitin sulfate, curcumin, and quercetin was effective in preventing recurrent UTIs, especially when paired with vaginal estrogen therapy. Although we recognized the synergy of these treatments, it’s essential to note that our exploration focused on the combined effects rather than isolating curcumin alone. Overall, this suggests a promising approach to managing recurrent infections in this demographic.
The participants were divided into three groups: one group received only vaginal estrogens, the second was treated with the natural supplement combination, and the third group received both the supplement and vaginal estrogens. We followed up with the participants over six and twelve months to assess the frequency of UTIs and overall symptom relief.
Our findings showed that the combination of hyaluronic acid, chondroitin sulfate, curcumin, and quercetin was effective in preventing recurrent UTIs, especially when paired with vaginal estrogen therapy. Although we recognized the synergy of these treatments, it’s essential to note that our exploration focused on the combined effects rather than isolating curcumin alone. Overall, this suggests a promising approach to managing recurrent infections in this demographic.
Read More
9
Curcumin inhibits UTI bacteria
Inhibition of biofilm development of uropathogens by curcumin - an anti-quorum sensing agent from Curcuma longa.
Highly relevant to UTI treatments
We examined the potential of curcumin, the active ingredient in turmeric, to combat urinary tract infections (UTIs), which are often caused by bacteria forming biofilms. This study specifically looked at how curcumin could interfere with the quorum sensing (QS) systems of uropathogens like Escherichia coli and Pseudomonas aeruginosa.
Our research found that curcumin effectively inhibited the formation of biofilms by these bacteria and was even able to disrupt existing mature biofilms. Using light and confocal laser scanning microscopy, we observed these effects firsthand.
Additionally, we noted that treatment with curcumin reduced important QS-dependent activities in these bacteria, such as exopolysaccharide and alginate production, as well as their swimming and swarming abilities. Remarkably, curcumin also increased the effectiveness of standard antibiotics against these uropathogens, making it a promising option for enhancing current UTI treatments.
Our research found that curcumin effectively inhibited the formation of biofilms by these bacteria and was even able to disrupt existing mature biofilms. Using light and confocal laser scanning microscopy, we observed these effects firsthand.
Additionally, we noted that treatment with curcumin reduced important QS-dependent activities in these bacteria, such as exopolysaccharide and alginate production, as well as their swimming and swarming abilities. Remarkably, curcumin also increased the effectiveness of standard antibiotics against these uropathogens, making it a promising option for enhancing current UTI treatments.
Read More
8
Curcumin complex shows antibacterial promise
Curcumin-sulfobutyl-ether beta cyclodextrin inclusion complex: preparation, spectral characterization, molecular modeling, and antimicrobial activity.
Strong relevance to UTI treatment
We explored the effectiveness of curcumin, a natural compound found in turmeric, as a potential treatment for urinary tract infections (UTIs). Given the rising concern over antibiotic resistance, it's crucial to investigate alternative therapies, and curcumin's remarkable properties have caught our attention.
In this study, we created a complex of curcumin with sulfobutyl ether-β-cyclodextrin to enhance its solubility and bioavailability. Our findings from phase solubility studies and spectral analysis showed that curcumin was successfully encapsulated within the cyclodextrin. This complex aimed to maximize curcumin's therapeutic potential and make it more effective against bacteria.
The antimicrobial effectiveness was tested through a disc diffusion method. Interestingly, we observed that the curcumin-cyclodextrin complex exhibited significant antimicrobial activity, showing a zone of inhibition against Escherichia coli and Staphylococcus aureus—two key bacteria involved in UTIs. This result was compelling since curcumin alone exhibited no antibacterial effect.
Ultimately, our study suggests that the curcumin-cyclodextrin complex holds promise as a potential alternative for treating UTIs. By offering a new strategy against bacterial infections, it could be a significant step in addressing antibiotic resistance.
In this study, we created a complex of curcumin with sulfobutyl ether-β-cyclodextrin to enhance its solubility and bioavailability. Our findings from phase solubility studies and spectral analysis showed that curcumin was successfully encapsulated within the cyclodextrin. This complex aimed to maximize curcumin's therapeutic potential and make it more effective against bacteria.
The antimicrobial effectiveness was tested through a disc diffusion method. Interestingly, we observed that the curcumin-cyclodextrin complex exhibited significant antimicrobial activity, showing a zone of inhibition against Escherichia coli and Staphylococcus aureus—two key bacteria involved in UTIs. This result was compelling since curcumin alone exhibited no antibacterial effect.
Ultimately, our study suggests that the curcumin-cyclodextrin complex holds promise as a potential alternative for treating UTIs. By offering a new strategy against bacterial infections, it could be a significant step in addressing antibiotic resistance.
Read More
8
Curcumin aids chronic UTI treatment
Intervention effect and mechanism of curcumin in chronic urinary tract infection in rats.
Direct focus on UTI treatment
In our study, we explored how curcumin, a compound found in turmeric, affects chronic urinary tract infections (UTIs) in rats. To investigate this, we set up three groups of experimental animals: a normal group, a model group that had chronic UTIs induced, and a curcumin group that received an injection of curcumin over 14 days.
We observed that curcumin treatment significantly improved the symptoms of chronic UTIs in the rats. Specifically, it helped protect renal function and reduced inflammation, as indicated by lower levels of inflammatory cytokines in the serum. Additionally, the study highlighted that curcumin influenced the expression of critical receptors related to immune response in the renal and bladder tissues.
Overall, our findings suggest that curcumin can be an effective option for managing chronic urinary tract infections by enhancing kidney health and minimizing inflammation.
We observed that curcumin treatment significantly improved the symptoms of chronic UTIs in the rats. Specifically, it helped protect renal function and reduced inflammation, as indicated by lower levels of inflammatory cytokines in the serum. Additionally, the study highlighted that curcumin influenced the expression of critical receptors related to immune response in the renal and bladder tissues.
Overall, our findings suggest that curcumin can be an effective option for managing chronic urinary tract infections by enhancing kidney health and minimizing inflammation.
Read More
7
Turmeric's role in UTIs
Potential Role of Curcumin Against Biofilm-Producing Organisms on the Skin: A Review.
Effectiveness linked to antibiotics
We explored how turmeric, particularly its active compound curcumin, may play a role in fighting urinary tract infections (UTIs). Curcumin has been celebrated for its antimicrobial properties, but understanding its specific effectiveness against UTIs remains essential.
The reviewed studies indicate that curcumin has shown promise when combined with antibiotics, demonstrating bactericidal efficacy in various clinical settings. However, we recognized that the focus primarily lay on its interactions with other treatments rather than isolation of curcumin’s specific effects on urinary tract infections alone.
While curcumin could offer potential benefits, it’s evident that more comprehensive research is needed to determine which organisms are most susceptible to curcumin and how we might effectively utilize it in UTI treatment. Overall, our findings underscore the importance of further investigation into turmeric’s role in this area.
The reviewed studies indicate that curcumin has shown promise when combined with antibiotics, demonstrating bactericidal efficacy in various clinical settings. However, we recognized that the focus primarily lay on its interactions with other treatments rather than isolation of curcumin’s specific effects on urinary tract infections alone.
While curcumin could offer potential benefits, it’s evident that more comprehensive research is needed to determine which organisms are most susceptible to curcumin and how we might effectively utilize it in UTI treatment. Overall, our findings underscore the importance of further investigation into turmeric’s role in this area.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
8.8
Significant improvement
Great doing the job. I have suffered from chronic infections in the pelvic area, and there has been significant improvement in treating my urinary tract infection.
8.3
Really good effect
I ordered it for my father, and he said it was great! It’s truly effective for treating urinary tract infection and inflammation.
